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The role of NMN in the body


DNA Double stranded
DNA plays a key role in the maintenance and repair of all cells in the body.

RNA Single stranded
RNA helps with cell signaling and protein production for the body.

The role of NMN
In the body, NMN converts into NR (nicotinamide riboside) that further converts into NAD+.
Learn moreNMN (Nicotinamide Mononucleotide)
NR (Nicotinamide Riboside)
NAD+ (Nicotinamide Adenine Dinucleotide)
What does NMN do in our cells?

Energy Source
NMN is important to the function of the mitochondrion, the power unit inside the cell.
Learn moreDNA repair & cancer prevention
NMN helps to upkeep PARP which is key for DNA repair, genomic stability, and programmed cell death.
Learn more

Increases sirtuin levels
a family of proteins that slows down aging, increases lifespan and regulates cellular health.
Learn moreWhy can't we easily supplement NAD+?

NAD (Nicotinamide adenine dinucleotide) is created from NMN and NR. However, NAD+ is highly unstable and this is why supplementing NMN is more effective.
Learn moreWhy you may want NMN

The levels of NMN and NAD drop by 50% by middle age and this is why we need to supplement it.
Learn moreWhat are the sources of NMN?
- From food, but usually it is not enough.
- Body's own production, but it is insufficent in middle age.

NMN taken with B12 (methylcobalamin) Most efficient
Why should you take B12 with NMN

B12 (methylcobalamin)
NMN requires methyl groups which are vital for DNA replication, detoxification and other important cellular processes. NMN, therefore, may deplete methyl groups within the body. B12 supplementation provides methyl building blocks for NMN intake within the body.
Learn moreBenefits

DNA Repair

Helps Immunity

Cancer Defense

Increases Metabolism

Increases Energy

Reduces Inflammation

Heart Health

Brain Health

Cellular Repair
What is NMN?
Nicotinamide mononucleotide ("NMN", "NAMN",
and "β-NMN") is a bioactive nucleotide, the organic compounds that serve as
building blocks for DNA and
RNA.
These are the molecules essential to all life and species reproduction!
The role of NMN
Inside our cells, the NMN molecule is further converted into another nucleotide, NAD+ (Nicotinamide Adenine Dinucleotide), which is the key source of energy for the body.
Energy Source
NAD is essential for cellular energy creation inside mitochondria, which play a central role in supplying cells with energy.
DNA repair & cancer prevention
NAD plays an important role in PARP, which stands for Poly (ADP-ribose) polymerase. PARP is a protein that is important for DNA repair, genetic stability, and programmed cell death (which is important in the body’s cancer defense system). Once again, without NAD, PARP would be ineffective. As life goes on and the body constantly regenerates, DNA has to replicate. The process of replication can be compared to copying an audio recording on an analog tape. With each copy the recording quality is lower, and the errors in transcription show as recording noise. In a young body, DNA transcription errors are efficiently repaired, however as the body ages and NAD levels decline, signs of aging (wrinkles, joint disease, organ disease and cancer) become more likely.
Increases sirtuin levels
NAD is also an important coenzyme that activates sirtuins, which are enzymes responsible for slowing down the aging process. In general, coenzymes serve as activation agents for enzymes. Their role can be compared to water in leavening sourdough bread. Without water, yeast will not multiply and the bread will not rise. Without coenzymes, some enzymes in the body won't be active.
What is Methylation?
Methylation is a simple biochemical reaction that is required for the process of DNA repair and also to reduce the levels of homocysteine and prevent blood vessel damage. Methylation also takes part in the production of feel good hormones and prevention of depression.
The conversion of NMN to NAD requires methylation and therefore we recommend supplementing methyl groups together with our NMNPure H+ supplement. The simplest and most effective way to do so is to supplement with vitamin B12 (methylcobalamin).
Why can't we easily supplement NAD+?
As the body reaches middle age, it's ability to produce NAD from vitamin B3 and other nutrients decreases, and the levels of NAD drop by half. This is one of the main causes of aging, decline in energy, chronic disease, decrease in immune function and failure of the immune system to destroy cancer cells. NMN has been in the forefront of the leading anti-aging research for more than a decade, first in yeast and then mammals and people.
What are the main symptoms of low NAD levels?
With the decline of NAD, the individual feels fatigued, their performance is lowered, muscles may be weaker, joints become stiffer, the immune system is less effective, inflammation in the blood vessels and tissues increases, and the brain and nervous system show signs of decline.